Thin primary cutaneous melanomas
نویسندگان
چکیده
منابع مشابه
Thin primary cutaneous melanomas: associated detection patterns, lesion characteristics, and patient characteristics.
BACKGROUND Public awareness and education may lead to the detection of thinner melanomas, which may result in a decrease in morbidity and mortality rates. Which detection patterns, lesion, and patient characteristics are associated with early detection? METHODS Using the University of Michigan prospective melanoma database, the detection patterns, lesion characteristics, and patient character...
متن کاملThin and thick primary cutaneous melanomas reveal distinct patterns of somatic copy number alterations
Cutaneous melanoma is one of the most aggressive type of skin tumor. Early stage melanoma can be often cured by surgery; therefore current management guidelines dictate a different approach for thin (<1mm) versus thick (>4mm) melanomas. We have carried out whole-exome sequencing in 5 thin and 5 thick fresh-frozen primary cutaneous melanomas. Unsupervised hierarchical clustering analysis of soma...
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Cutaneous melanomas has become one of the most discussed and studied tumor because its particular immunologic development but also its increasing rate worldwide in the last decades. Even thought many patients are diagnosed at an early stage, the death rate continues to rise due to the increasing incidence of more advanced lesions. The aim of this study is to detect apoptosis in 30 cases of cuta...
متن کاملClinical appearance of cutaneous melanomas.
Brown and black spots are present on the skin of all people. Melanomas compromise only a very small percentage of all such pigmented lesions but are responsible for most of the deaths and illness caused by pigment cells. Three types of melanomas can be distinguished from their clinical, histologic, and biologic characteristics: lentigo maligna, superficial spreading melanoma, and nodular melano...
متن کاملCutaneous melanomas associated with nevi.
OBJECTIVE To determine the frequency of and the histologic and clinical factors associated with melanoma existing in histologic contiguity with a nevus. DESIGN Pathology reports from melanomas collected from January 1, 1993, to December 31, 1997, were retrospectively reviewed. SETTING Independent, community-based dermatopathology laboratory. PATIENTS A total of 1606 patients with a histol...
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ژورنال
عنوان ژورنال: Cancer
سال: 2002
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.10880